PLATFORM EVIDENCE

The evidence
behind the platform.

Gathering peer-reviewed clinical data, institutional recognition, and key media updates backing our computational architecture.

Peer-Reviewed / Clinical

Peer-reviewed.
Clinically validated.

Nature Medicine · 2026

Co-clinical validation of agentic targeting frameworks

Rigorous multi-cohort evaluation confirming the accuracy and clinical utility of autonomous variant interpretation engines across complex oncology cohorts.

Digital Twin Casebook
Lancet Digital Health · 2025

Targeted therapeutics vs. autonomous genomic modeling

A comprehensive comparative analysis benchmarking predictive precision care pipelines against conventional treatment decision trees.

Digital Twin Casebook
ASCO Abstract · 2026

Digital twins in oncology: Real-world therapeutic pipelines

Demonstrating actionable therapeutic insight improvements via live pipeline simulations mapping real-time patient progression markers.

Digital Twin Casebook Deep Precision™ NGS
Frontiers in Genetics · 2025

Machine learning optimizations in variant filtering

Iterative neural model applications achieving unprecedented false-positive reductions across high-throughput raw genomics sequence inputs.

Digital Twin Casebook Deep Precision™ NGS
Media Reporting

GeneSilico
in the news.

Sep 2024
Medrxiv

Improved precision oncology question-answering using agentic LLM

Discover how GeneSilico’s gSage revolutionizes LLMs in precision oncology, offering accurate and personalized breast cancer treatment recommendations.

2026 June
India education diary

Prof. Debarka Sengupta Honored With Merck Young Scientist Award, 2023

The award ceremony, held in Bangalore on November 24th, 2023, stands as a significant milestone in Prof. Sengupta’s illustrious scientific journey, highlighting his unwavering dedication and outstanding contributions to advancing AI applications in cancer research.

Sep 2022
Nature Communications

Gene expression based inference of cancer drug sensitivity

Predictive modeling approach to infer treatment response in cancers.

Nov 2022
Communications biology

Microfluidic live tracking and transcriptomics of cancer-immune cell doublets link intercellular proximity and gene regulation

Examining how cancer and immune cells interact and influence genes using microfluidic technology.

Nov 2017
Pubmed

Decoding critical long non-coding RNA in ovarian cancer epithelial-to-mesenchymal transition

Discover how the lncRNA DNM3OS drives metastasis in ovarian cancer by regulating EMT, revealing new therapeutic possibilities for improving patient outcomes.

Awards & Recognition

Recognized by
leading institutions.

2025

Nature Publication

Peer-reviewed research published in Nature — the world's leading scientific journal detailing clinical framework utility.

2025

Humboldt Grant

Alexander von Humboldt Stiftung research award for breakthrough contributions to autonomous oncology AI modeling.

2025

ICMR Validation

Selected for India's national clinical validation study across healthcare infrastructure by the Indian Council of Medical Research.

2024–2026

10 Patents Filed

Ten core utility patents covering the causal AI computation engines, Digital Twin construction models, and sequence workflows.

2025

Govt. Recognition

Formally recognized for high-impact contributions engineered to scale national healthcare artificial intelligence infrastructure.

2026

Epic Certification

Certified on Epic Marketplace for native EHR data structure integration across high-throughput clinical networks.

Blog & Insights

Thinking about
precision oncology.

Science 8 Min Read

Why causal AI beats correlation for cancer therapy selection

Most oncology AI predicts from population patterns. We explain why that fundamentally misses the point — and what causal reasoning changes.

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Clinical 6 Min Read

How early resistance detection changes the economics of cancer care

Catching resistance 7 weeks earlier doesn't just save response time — it changes the cost structure of an entire treatment course.

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Patient Care 5 Min Read

What patients actually want from a cancer AI companion

We spoke to 40 patients across India about what they needed most during treatment. The answers surprised us — and shaped MyCasebook.

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See the science
in the clinic.

Request a demo or explore what each product does.